LEADERSHIP TEAM

Principal Investigator, Chief Medical Officer, President & CEO
Arthur Cabrera, M.D.
Dr. Cabrera leads all PRL clinical research initiatives. With deep expertise in human physiology and over two decades of clinical anesthesiology experience, he has overseen hundreds of clinical trials since 2016, particularly in the areas of blood pressure, pulse oximetry, respiratory rate, and temperature monitoring. His work in hypoxia and hemodynamic research has included the placement of approximately 3,000 arterial catheters since 2022. Most recently, he has played a key role in the working group for the upcoming ISO 81060-7 standard for cuffless blood pressure devices and led the clinical investigation that supported FDA approval of the first over-the-counter cuffless blood pressure monitor in the U.S.
In addition to his research leadership, Dr. Cabrera is a board-certified anesthesiologist who has practiced in Colorado since 1995. Over his tenure, he held numerous leadership positions including Department Chairman, CFO/COO, and served on the Medical Executive Committee. He was instrumental in growing a private anesthesia practice into a larger, multidisciplinary organization that was eventually acquired by a national group. Throughout his career, Dr. Cabrera has remained committed to clinical excellence, innovation, and advancing patient care through rigorous research and medical device validation.

Chief Operating Officer
Lana Brennan
Lana exceeds over 25 years of experience in healthcare and over three decades as a small business owner. She is responsible for operational leadership, strategic planning, and organizational growth, with a focus on ensuring clinical and business functions are aligned for efficiency, compliance, and quality outcomes.
Her background combines clinical expertise with entrepreneurial management, bringing a unique perspective to healthcare operations. Lana holds a Bachelor of Science in Nursing and a Master’s in Business Administration. She is a licensed Registered Nurse and certified in Neonatal Intensive Care.

Chief Clinical Research Officer
Anne Fedor
Anne provides extensive experience in medical device research, specializing in the validation of non-invasive blood pressure technologies. She oversees the design and execution of clinical studies that ensure data accuracy, regulatory compliance, and real-world relevance. Her work supports device developers in achieving FDA clearance and demonstrating clinical performance.
Anne’s background includes 15 years at a medical device research laboratory, where she played a key role in establishing and expanding its blood pressure testing program. Her expertise in non-invasive device validation is grounded in hands-on clinical experience and a deep understanding of regulatory requirements.
She holds a Bachelor’s degree from the University of Colorado Boulder and has been a licensed Registered Nurse since 2008.

Quality Assurance Manager; Clinical Study Monitor
Nanette Cabrera Colip, M.D.
Nanette oversees compliance across all clinical trials conducted at PRL. She ensures that studies adhere to ISO 14155, ICH E6 (R3), and Good Clinical Practice (GCP) standards, maintaining the integrity and reliability of clinical data through rigorous quality systems and internal oversight.
Dr. Colip brings over 20 years of experience in healthcare, including more than a decade as a practicing anesthesiologist and department head. Since 2022, she has worked in clinical research, applying her background in medicine and quality systems to trial monitoring, risk management, internal auditing, and staff training.
She earned her MD from the University of Kansas Medical Center and completed her anesthesia residency at the University of Colorado Health Sciences Center, where she served as Chief Resident. She also holds a B.A. in Human Biology, magna cum laude, from the University of Kansas. Dr. Colip is a member of the American Society of Anesthesiologists and the Association of Clinical Research Professionals.

Chief Techology Officer
Sara Thiele
Sara is responsible for the technical oversight of clinical trials and device validation. She works closely with sponsors to ensure technologies align with clinical research goals and regulatory standards, translating complex technical requirements into actionable insights for cross-functional teams. She also leads and supports internal technology initiatives that enhance data integrity and operational efficiency.
Sara brings over 14 years of experience in medical device development and clinical research. As a Senior Mechanical Engineer, she led the design of Class II and III medical devices, and later served as Technical Director overseeing study design, device integration, and data analysis for clinical trials.
Her areas of expertise include medical device validation (FDA, ISO, IEC), wearable and cuffless technologies, technical protocol development, secure data management, rapid prototyping, and risk management strategies such as FMEA and CAPA. Sara holds a B.S. in Mechanical Engineering from the University of Colorado.
SPECIALISTS

IRB Specialist
Amy Smith
Amy is a CCRP® (certified clinical research professional) with SOCRA and an active member with ACRP currently studying for her CRA certification. She has been involved in medical device research for close to 9 years working with minimal risk and non-significant Class II medical device studies in the life sciences realm of clinical research. Amy began as a research technician, but her niche is compliance and working with multiple IRB’s. She assists with IRB submissions, policy and procedure review, document revision control and study monitor. She also strives to keep learning and stay informed of regulatory and industry updates.

Senior Data Analysist
Carolyn Cohen
Carolyn brings over 10 years of experience in medical device clinical research. She designs validation protocols and performs statistical analyses to support FDA 510(k) submissions for pulse oximeters, blood pressure monitors, and other wellness technologies. Her expertise includes protocol development, QMS documentation, and analytical methods such as Bland-Altman analysis. Carolyn’s background includes 9 years as a Senior Clinical Study Coordinator and Data Analyst, and 2 years as a technical researcher focused on pulse oximetry. She holds a B.S. in Biological Sciences from Colorado State University.

Scheduling and Recruitment Manager
Misty Demery
Misty oversees participant recruitment, scheduling, and engagement for clinical research studies. She works closely with sponsors to identify required phenotypes, supports enrollment goals, and represents the lab at community events to foster participant outreach and study growth.
With 10 years of experience in clinical research, Misty has held roles in both study coordination and recruitment. She brings expertise in managing study timelines, developing recruitment strategies, maintaining participant databases, and optimizing visit scheduling across complex study protocols. She also trains recruitment staff and ensures all participant outreach is conducted ethically and in accordance with informed consent requirements.
Misty holds a B.A. in Psychology and is a certified Medical Assistant. She is a member of the Association of Clinical Research Professionals (ACRP).